The Amarillo Venom are a professional indoor football team based in Amarillo, Texas. They play their home games at the Amarillo Civic Center and are members of American Indoor Football as of August 2024. The Venom began play in 2004 as the Amarillo Dusters, a charter member of the Intense Football League, a small indoor football league based in Texas. They won the championship in their first and only season with the Intense Football League.

In 2005, the Dusters became the first team to leave the Intense Football League and join the AF2, the minor league of the Arena Football League, where they played for four seasons until the AF2's folding in 2009. At that point, the team held a fan vote as to whether to join some of their AF2 brethren in the new Arena Football 1 (later gaining rights to the name as Arena Football League) or enjoy numerous Texas rivalries in the Indoor Football League. In 2009, it was announced that the Dusters would be moving to the Indoor Football League for the 2010 season. It was then announced that the Dusters would have to be renamed because the Arena Football League owned the rights to the Dusters name and logo and the team became the Venom.

The Venom then joined the Lone Star Football League for the 2012 season, which eventually merged into Champions Indoor Football (CIF) prior to the 2015 season. Prior to the 2021 season, the Venom withdrew from the CIF and later formed the Arena Football Association for the 2022 season. However, the team suspended operations in February 2022.